Biomaterials and Clinical Research Laboratory- BioClinLab
Research group Leader
Prof. Antonio Scarano
Department of Medical, Oral and Biotechnological Sciences
RESEARCH GROUP ACTIVITY
The research group provides full-service integrated research activity for human clinical trials, animal studies and cyclical fatigue mechanical tests partnered by sponsors in the pharmaceutical and biotechnological industries for biomaterials and medical devices development.
The assets of the group span across several fields of medicine and dentistry and address a wide range of therapeutic areas.
The activities also include translational research in the field of aesthetic medicine, with particular regard to the development of innovative treatments for stress-related changes and aging of the facial bones and skin.
Scarano, A., Di Carlo, F., Quaranta, M., Piattelli, A. Bone response to zirconia ceramic implants: an experimental study in rabbits. (2003) The Journal of oral implantology, 29 (1), pp. 8-12. doi: 10.1563/1548-1336(2003)029%3C0008:BRTZCI%3E2.3.CO;2
Piattelli, A., Vrespa, G., Petrone, G., Iezzi, G., Annibali, S., Scarano, A.
Role of the microgap between implant and abutment: A retrospective histologic evaluation in monkeys (2003) Journal of Periodontology, 74 (3), pp. 346-352. doi: 10.1902/jop.2003.74.3.346
Scarano, A., Piattelli, M., Caputi, S., Favero, G.A., Piattelli, A. Bacterial adhesion on commercially pure titanium and zirconium oxide disks: An in vivo human study (2004) Journal of Periodontology, 75 (2), pp. 292-296. doi: 10.1902/jop.2004.75.2.292
Scarano, A., Degidi, M., Iezzi, G., Pecora, G., Piattelli, M., Orsini, G., Caputi, S., Perrotti, V., Mangano, C., Piattelli, A. Maxillary sinus augmentation with different biomaterials: A comparative histologic and histomorphometric study in man (2006) Implant Dentistry, 15 (2), pp. 197-207. doi: 10.1097/01.id.0000220120.54308.f3
Scarano A, Valbonetti L, Marchetti M, Lorusso F, Ceccarelli M. Soft Tissue Augmentation of the Face With Autologous Platelet-Derived Growth Factors and Tricalcium Phosphate. Microtomography Evaluation of Mice. J Craniofac Surg. 2016 Jul;27(5):1212-4. doi: 10.1097/SCS.0000000000002712.
Scarano A, Lorusso F, Staiti G, Sinjari B, Tampieri A, Mortellaro C. Sinus Augmentation with Biomimetic Nanostructured Matrix: Tomographic, Radiological, Histological and Histomorphometrical Results after 6 Months in Humans. Front Physiol. 2017 Aug 3;8:565. doi: 10.3389/fphys.2017.00565.
Scarano A, Crincoli V, Di Benedetto A, Cozzolino V, Lorusso F, Podaliri Vulpiani M, Grano M, Kalemaj Z, Mori G, Grassi FR. Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular "Critical Size" Defect. Stem Cells Int. 2017;2017:9082869. doi: 10.1155/2017/9082869. doi: 10.1155/2017/9082869
Scarano A, Murmura G, Vantaggiato G, Lauritano D, Silvestre-Rangil J, DI Cerbo A, Lorusso F. Delayed expansion of atrophic mandible (deam): a case report. Oral Implantol (Rome). 2017 Sep 27;10(2):190-196. doi: 10.11138/orl/2017.10.2.190. doi: 10.11138/orl/2017.10.2.190
Scarano A, Sinjari B, Murmura G, Lorusso F. Neurosensory Disturbance of the Inferior Alveolar Nerve After 3025 Implant Placements. Implant Dent. 2017 Oct;26(5):735-743. doi: 10.1097/ID.0000000000000651. doi: 10.1097/ID.0000000000000651
Scarano A, Crocetta E, Quaranta A, Lorusso F. Influence of the Thermal Treatment to Address a Better Osseointegration of Ti6Al4V Dental Implants: Histological and Histomorphometrical Study in a Rabbit Model. Biomed Res Int. 2018 Jun 27;2018: 2349698. doi: 10.1155/2018/2349698.
Scarano A, Lorusso F, Arcangelo M, D'Arcangelo C, Celletti R, de Oliveira PS. Lateral Sinus Floor Elevation Performed with Trapezoidal and Modified Triangular Flap Designs: A Randomized Pilot Study of Post-Operative Pain Using Thermal Infrared Imaging. Int J Environ Res Public Health. 2018 Jun 16;15(6). pii: E1277. doi: 10.3390/ijerph15061277.
Scarano A, Lorusso F, Orsini T, Morra M, Iviglia G, Valbonetti L. Biomimetic Surfaces Coated with Covalently Immobilized Collagen Type I: An X-Ray Photoelectron Spectroscopy, Atomic Force Microscopy, Micro-CT and Histomorphometrical Study in Rabbits. Int J Mol Sci. 2019 Feb 8;20(3). pii: E724. doi: 10.3390/ijms20030724
Scarano A, Lorusso F, Di Cerbo A, Lucchina AG, Carinci F. Eradication of hairy mouth after oncological resection of the tongue and floor mouth using a diode laser 808 nm. Postoperative pain assessment using thermal infrared imaging. Lasers Surg Med. 2019 Aug;51(6):516-521. doi: 10.1002/lsm.23054.
Scarano A, Piattelli A, Quaranta A, Lorusso F. Bone Response to Two Dental Implants with Different Sandblasted/Acid-Etched Implant Surfaces: A Histological and Histomorphometrical Study in Rabbits. Biomed Res Int. 2017;2017:8724951. doi: 10.1155/2017/8724951.
Scarano A, Carinci F, Festa F, Candotto V, Amore R, Lorusso F. Periauricular wrinkles removed with voltaic arc dermabrasion (Atmospheric Plasma technique). J Cosmet Dermatol. 2019 Oct 26. doi: 10.1111/jocd.13204.
Petrini M, Spoto G, Scarano A, D'Arcangelo C, Tripodi D, Di Fermo P, D'Ercole S. Near-infrared LEDS provide persistent and increasing protection against E. faecalis. J Photochem Photobiol B. 2019 Aug;197:111527. doi: 10.1016/j.jphotobiol.2019.111527.
Scarano A, Lorusso F, Noumbissi S. Infrared Thermographic Evaluation of Temperature Modifications Induced during Implant Site Preparation with Steel vs. Zirconia Implant Drill. J Clin Med. 2020 Jan 5;9(1). pii: E148. doi: 10.3390/jcm9010148.
Scarano A, Petrini M, Mastrangelo F, Noumbissi S, Lorusso F. The Effects of Liquid Disinfection and Heat Sterilization Processes on Implant Drill Roughness: Energy Dispersion X-ray Microanalysis and Infrared Thermography. J Clin Med. 2020 Apr 4;9(4). pii: E1019. doi: 10.3390/jcm9041019.
